Ontology highlight
ABSTRACT:
SUBMITTER: Vicidomini G
PROVIDER: S-EPMC2635477 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Vicidomini Giuseppe G Gagliani Maria C MC Canfora Michela M Cortese Katia K Frosi Fabio F Santangelo Clara C Di Fiore Pier Paolo PP Boccacci Patrizia P Diaspro Alberto A Tacchetti Carlo C
Traffic (Copenhagen, Denmark) 20080809 11
Correlative light/electron microscopy (CLEM) allows the simultaneous observation of a given subcellular structure by fluorescence light microscopy (FLM) and electron microscopy. The use of this approach is becoming increasingly frequent in cell biology. In this study, we report on a new high data output CLEM method based on the use of cryosections. We successfully applied the method to analyze the structure of rough and smooth Russell bodies used as model systems. The major advantages of our met ...[more]