Ontology highlight
ABSTRACT:
SUBMITTER: Barnes KM
PROVIDER: S-EPMC2635526 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Barnes Kimberly M KM Evenson Jacqueline K JK Raines Anna M AM Sunde Roger A RA
The Journal of nutrition 20081223 2
Dietary selenium (Se) requirements in rats have been based largely upon glutathione peroxidase-1 (Gpx1) enzyme activity and Gpx1 mRNA levels can also be used to determine Se requirements. The identification of the complete selenoprotein proteome suggests that we might identify additional useful molecular biomarkers for assessment of Se status. To characterize Se regulation of the entire rat selenoproteome, weanling male rats were fed a Se-deficient diet (<0.01 microg Se/g) supplemented with grad ...[more]