Ontology highlight
ABSTRACT:
SUBMITTER: Montez T
PROVIDER: S-EPMC2635782 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Montez Teresa T Poil Simon-Shlomo SS Jones Bethany F BF Manshanden Ilonka I Verbunt Jeroen P A JP van Dijk Bob W BW Brussaard Arjen B AB van Ooyen Arjen A Stam Cornelis J CJ Scheltens Philip P Linkenkaer-Hansen Klaus K
Proceedings of the National Academy of Sciences of the United States of America 20090121 5
Encoding and retention of information in memory are associated with a sustained increase in the amplitude of neuronal oscillations for up to several seconds. We reasoned that coordination of oscillatory activity over time might be important for memory and, therefore, that the amplitude modulation of oscillations may be abnormal in Alzheimer disease (AD). To test this hypothesis, we measured magnetoencephalography (MEG) during eyes-closed rest in 19 patients diagnosed with early-stage AD and 16 a ...[more]