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Electron transfer-initiated Diels-Alder cycloadditions of 2'-hydroxychalcones.

ABSTRACT: An efficient approach to cyclohexenyl chalcones employing highly electron rich 2'-hydroxychalcone dienophiles via electron transfer-initiated Diels-Alder cycloaddition is described. Using the methodology, the total synthesis of nicolaiodesin C has been accomplished.

SUBMITTER: Cong H

PROVIDER: S-EPMC2635952 | biostudies-literature | 2008 Jul

REPOSITORIES: biostudies-literature

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Electron transfer-initiated Diels-Alder cycloadditions of 2'-hydroxychalcones.

Cong Huan H Ledbetter Dustin D Rowe Gerard T GT Caradonna John P JP Porco John A JA

Journal of the American Chemical Society 20080625 29

An efficient approach to cyclohexenyl chalcones employing highly electron rich 2'-hydroxychalcone dienophiles via electron transfer-initiated Diels-Alder cycloaddition is described. Using the methodology, the total synthesis of nicolaiodesin C has been accomplished. ...[more]

PMID: 18576647

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