Ontology highlight
ABSTRACT:
SUBMITTER: Bendezu FO
PROVIDER: S-EPMC2637328 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Bendezú Felipe O FO Hale Cynthia A CA Bernhardt Thomas G TG de Boer Piet A J PA
The EMBO journal 20081211 3
The bacterial MreB actin cytoskeleton is required for cell shape maintenance in most non-spherical organisms. In rod-shaped cells such as Escherichia coli, it typically assembles along the long axis in a spiral-like configuration just underneath the cytoplasmic membrane. How this configuration is controlled and how it helps dictate cell shape is unclear. In a new genetic screen for cell shape mutants, we identified RodZ (YfgA) as an important transmembrane component of the cytoskeleton. Loss of ...[more]