Ontology highlight
ABSTRACT:
SUBMITTER: Archer GS
PROVIDER: S-EPMC2637358 | biostudies-literature | 2003 Aug
REPOSITORIES: biostudies-literature
Archer Greg S GS Dindot Scott S Friend Ted H TH Walker Shawn S Zaunbrecher Gretchen G Lawhorn Bruce B Piedrahita Jorge A JA
Biology of reproduction 20030416 2
Cloning by somatic cell nuclear transfer can result in the birth of animals with phenotypic and gene expression abnormalities. We compared adult cloned pigs and adult pigs from naturally bred control females using a series of physiological and genetic parameters, including detailed methylation profiles of selected genomic regions. Phenotypic and genetic analyses indicated that there are two classes of traits, one in which the cloned pigs have less variation than controls and another characterize ...[more]