Ontology highlight
ABSTRACT:
SUBMITTER: Graham RL
PROVIDER: S-EPMC2637536 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Graham Rachel L RL Sparks Jennifer S JS Eckerle Lance D LD Sims Amy C AC Denison Mark R MR
Virus research 20070329 1
Much progress has been made in understanding the role of structural and accessory proteins in the pathogenesis of severe acute respiratory syndrome coronavirus (SARS-CoV) infections. The SARS epidemic also brought new attention to the proteins translated from ORF1a and ORF1b of the input genome RNA, also known as the replicase/transcriptase gene. Evidence for change within the ORF1ab coding sequence during the SARS epidemic, as well as evidence from studies with other coronaviruses, indicates th ...[more]