Ontology highlight
ABSTRACT:
SUBMITTER: Silver MA
PROVIDER: S-EPMC2640421 | biostudies-literature | 2008 Dec
REPOSITORIES: biostudies-literature
Silver Michael A MA Shenhav Amitai A D'Esposito Mark M
Neuron 20081201 5
Animal studies have shown that acetylcholine decreases excitatory receptive field size and spread of excitation in early visual cortex. These effects are thought to be due to facilitation of thalamocortical synaptic transmission and/or suppression of intracortical connections. We have used functional magnetic resonance imaging (fMRI) to measure the spatial spread of responses to visual stimulation in human early visual cortex. The cholinesterase inhibitor donepezil was administered to normal hea ...[more]