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Si-based benzylic 1,4-rearrangement/cyclization reaction.

ABSTRACT: The trans-selective hydrosilylation of ynones (1) yields beta-silylated enones (2) that undergo a benzylic 1,4-rearrangement/cyclization reaction in the presence of base, yielding 2,5-dihydro-1,2-oxasiloles (3).

SUBMITTER: Trost BM

PROVIDER: S-EPMC2640427 | biostudies-literature | 2009 Feb

REPOSITORIES: biostudies-literature

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Si-based benzylic 1,4-rearrangement/cyclization reaction.

Trost Barry M BM Bertogg Andreas A

Organic letters 20090201 3

The trans-selective hydrosilylation of ynones (1) yields beta-silylated enones (2) that undergo a benzylic 1,4-rearrangement/cyclization reaction in the presence of base, yielding 2,5-dihydro-1,2-oxasiloles (3). ...[more]

PMID: 19125665

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