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The AAA+ superfamily of functionally diverse proteins.


ABSTRACT: SUMMARY: The AAA+ superfamily is a large and functionally diverse superfamily of NTPases that are characterized by a conserved nucleotide-binding and catalytic module, the AAA+ module. Members are involved in an astonishing range of different cellular processes, attaining this functional diversity through additions of structural motifs and modifications to the core AAA+ module.

SUBMITTER: Snider J 

PROVIDER: S-EPMC2643927 | biostudies-literature | 2008

REPOSITORIES: biostudies-literature

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The AAA+ superfamily of functionally diverse proteins.

Snider Jamie J   Thibault Guillaume G   Houry Walid A WA  

Genome biology 20080430 4


<h4>Summary</h4>The AAA+ superfamily is a large and functionally diverse superfamily of NTPases that are characterized by a conserved nucleotide-binding and catalytic module, the AAA+ module. Members are involved in an astonishing range of different cellular processes, attaining this functional diversity through additions of structural motifs and modifications to the core AAA+ module. ...[more]

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