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Protein identification pipeline for the homology-driven proteomics.


ABSTRACT: Homology-driven proteomics is a major tool to characterize proteomes of organisms with unsequenced genomes. This paper addresses practical aspects of automated homology-driven protein identifications by LC-MS/MS on a hybrid LTQ Orbitrap mass spectrometer. All essential software elements supporting the presented pipeline are either hosted at the publicly accessible web server, or are available for free download.

SUBMITTER: Junqueira M 

PROVIDER: S-EPMC2644553 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature

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Protein identification pipeline for the homology-driven proteomics.

Junqueira Magno M   Spirin Victor V   Balbuena Tiago Santana TS   Thomas Henrik H   Adzhubei Ivan I   Sunyaev Shamil S   Shevchenko Andrej A  

Journal of proteomics 20080712 3


Homology-driven proteomics is a major tool to characterize proteomes of organisms with unsequenced genomes. This paper addresses practical aspects of automated homology-driven protein identifications by LC-MS/MS on a hybrid LTQ Orbitrap mass spectrometer. All essential software elements supporting the presented pipeline are either hosted at the publicly accessible web server, or are available for free download. ...[more]

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