Ontology highlight
ABSTRACT:
SUBMITTER: Osawa M
PROVIDER: S-EPMC2645864 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Osawa Masaki M Anderson David E DE Erickson Harold P HP
Science (New York, N.Y.) 20080417 5877
FtsZ is a tubulin homolog and the major cytoskeletal protein in bacterial cell division. It assembles into the Z ring, which contains FtsZ and a dozen other division proteins, and constricts to divide the cell. We have constructed a membrane-targeted FtsZ (FtsZ-mts) by splicing an amphipathic helix to its C terminus. When mixed with lipid vesicles, FtsZ-mts was incorporated into the interior of some tubular vesicles. There it formed multiple Z rings that could move laterally in both directions a ...[more]