Ontology highlight
ABSTRACT:
SUBMITTER: Blizard DA
PROVIDER: S-EPMC2646459 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Blizard David A DA Lionikas Arimantas A Vandenbergh David J DJ Vasilopoulos Terrie T Gerhard Glenn S GS Griffith James W JW Klein Laura C LC Stout Joseph T JT Mack Holly A HA Lakoski Joan M JM Larsson Lars L Spicer Jeanne M JM Vogler George P GP McClearn Gerald E GE
Physiological genomics 20081209 3
A quantitative trait locus (QTL) approach was used to define the genetic architecture underlying variation in systolic blood pressure (SBP) and heart rate (HR), measured indirectly on seven occasions by the tail cuff procedure. The tests were conducted in 395 F(2) adult mice (197 males, 198 females) derived from a cross of the C57BL/6J (B6) and DBA/2J (D2) strains and in 22 BXD recombinant-inbred (RI) strains. Interval mapping of F(2) data for the first 5 days of measurement nominated one statis ...[more]