Ontology highlight
ABSTRACT:
SUBMITTER: Kotecha N
PROVIDER: S-EPMC2647559 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
Kotecha Nikesh N Flores Nikki J NJ Irish Jonathan M JM Simonds Erin F EF Sakai Debbie S DS Archambeault Sophie S Diaz-Flores Ernesto E Coram Marc M Shannon Kevin M KM Nolan Garry P GP Loh Mignon L ML
Cancer cell 20081001 4
Progress in understanding the molecular pathogenesis of human myeloproliferative disorders (MPDs) has led to guidelines incorporating genetic assays with histopathology during diagnosis. Advances in flow cytometry have made it possible to simultaneously measure cell type and signaling abnormalities arising as a consequence of genetic pathologies. Using flow cytometry, we observed a specific evoked STAT5 signaling signature in a subset of samples from patients suspected of having juvenile myelomo ...[more]