Genetics of sarcoidosis: candidate genes and genome scans.
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ABSTRACT:
SUBMITTER: Iannuzzi MC
PROVIDER: S-EPMC2647608 | biostudies-literature | 2007 Jan
REPOSITORIES: biostudies-literature
Publications
Genetics of sarcoidosis: candidate genes and genome scans.
Iannuzzi Michael C MC Rybicki Benjamin A BA
Proceedings of the American Thoracic Society 20070101 1
Human leukocyte antigen class II allele associations and T-cell receptor beta chain bias in sarcoidosis suggest a specific disease-triggering antigen exposure in a genetically susceptible host. The cause of sarcoidosis has been elusive, but genetics provides one of the few promising avenues to further our understanding. We review the association studies and genome scans used to identify the genes involved in sarcoidosis. ...[more]
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