Ontology highlight
ABSTRACT:
SUBMITTER: de Bruijn I
PROVIDER: S-EPMC2648375 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
de Bruijn I I Raaijmakers J M JM
Journal of bacteriology 20081229 6
Cyclic lipopeptides produced by Pseudomonas species exhibit potent surfactant and broad-spectrum antibiotic properties. Their biosynthesis is governed by large multimodular nonribosomal peptide synthetases, but little is known about the genetic regulatory network. This study provides, for the first time, evidence that the serine protease ClpP regulates the biosynthesis of massetolides, cyclic lipopeptides involved in swarming motility, biofilm formation, and antimicrobial activity of Pseudomonas ...[more]