Ontology highlight
ABSTRACT:
SUBMITTER: Zhang L
PROVIDER: S-EPMC2648626 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Zhang Lixin L Reddi Usha U Srinivasan Usha U Li Sheng S Borchardt Stephanie M SM Pillai Parvathy P Mehta Puja P Styka Anne N AN Debusscher Joan J Marrs Carl F CF Foxman Betsy B
Interdisciplinary perspectives on infectious diseases 20080225
Many bacterial species function as both commensals and pathogens; we used this dual nature to develop a high-throughput molecular epidemiological approach to identifying bacterial virulence genes. We applied our approach to Group B Streptococcus (GBS). Three representative commensal and one invasive GBS isolates were selected as tester strains from a population-based collection. We used microarray-based comparative genomic hybridization to identify open reading frames (ORFs) present in two seque ...[more]