Ontology highlight
ABSTRACT:
SUBMITTER: Stagg SM
PROVIDER: S-EPMC2649882 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Cell 20080801 3
Using cryo-electron microscopy, we have solved the structure of an icosidodecahedral COPII coat involved in cargo export from the endoplasmic reticulum (ER) coassembled from purified cargo adaptor Sec23-24 and Sec13-31 lattice-forming complexes. The coat structure shows a tetrameric assembly of the Sec23-24 adaptor layer that is well positioned beneath the vertices and edges of the Sec13-31 lattice. Fitting the known crystal structures of the COPII proteins into the density map reveals a flexibl ...[more]