Ontology highlight
ABSTRACT:
SUBMITTER: Milne RL
PROVIDER: S-EPMC2651585 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
Genome medicine 20090122 1
It has been established that heterozygous carriers of ataxia-telangiectasia-causing mutations in the ATM gene are at approximately two-fold higher risk of breast cancer. Several studies have attempted to assess the potential implication of the gene's more common variants in breast cancer susceptibility. Three large case-control studies have consistently found no evidence of association for variants with minor allele frequency greater than 5%. Other studies have evaluated associations for coding ...[more]