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Catalytic redox-initiated glycolate aldol additions of silyl glyoxylates.

ABSTRACT: Lanthanide triisopropoxides catalyze a rapid, tandem MPV reduction/Brook rearrangement/aldol sequence between silyl glyoxylates and aldehydes that achieves catalytic turnover through alkoxide transfer from a strain-release Lewis acidic silacycle.

SUBMITTER: Greszler SN

PROVIDER: S-EPMC2651742 | biostudies-literature | 2009 Feb

REPOSITORIES: biostudies-literature

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Catalytic redox-initiated glycolate aldol additions of silyl glyoxylates.

Greszler Stephen N SN Johnson Jeffrey S JS

Organic letters 20090201 4

Lanthanide triisopropoxides catalyze a rapid, tandem MPV reduction/Brook rearrangement/aldol sequence between silyl glyoxylates and aldehydes that achieves catalytic turnover through alkoxide transfer from a strain-release Lewis acidic silacycle. ...[more]

PMID: 19161319

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