Ontology highlight
ABSTRACT:
SUBMITTER: Kelker MS
PROVIDER: S-EPMC2652124 | biostudies-literature | 2009 Jan
REPOSITORIES: biostudies-literature
Kelker Matthew S MS Page Rebecca R Peti Wolfgang W
Journal of molecular biology 20081101 1
Protein phosphatase 1 occurs in all tissues and regulates many pathways, ranging from cell-cycle progression to carbohydrate metabolism. Many naturally occurring, molecular toxins modulate PP1 activity, though the exact mechanism of this differential regulation is not understood. A detailed elucidation of these interactions is crucial for understanding the cellular basis of phosphatase function and signaling pathways but, more importantly, they can serve as the basis for highly specific therapeu ...[more]