Ontology highlight
ABSTRACT:
SUBMITTER: Czerwinski EW
PROVIDER: S-EPMC2653420 | biostudies-literature | 2005 Feb
REPOSITORIES: biostudies-literature
The Journal of biological chemistry 20041110 5
Pollen from cedar and cypress trees is a major cause of seasonal hypersensitivity in humans in several regions of the Northern Hemisphere. We report the first crystal structure of a cedar allergen, Jun a 1, from the pollen of the mountain cedar Juniperus ashei (Cupressaceae). The core of the structure consists primarily of a parallel beta-helix, which is nearly identical to that found in the pectin/pectate lyases from several plant pathogenic microorganisms. Four IgE epitopes mapped to the surfa ...[more]