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Hexadecameric self-assembled dendrimers built from 2'-deoxyguanosine derivatives.


ABSTRACT: Herein we describe the construction of hexadecameric self-assembled dendrimers (SADs) using a series of dendronized 8-(m-acetylphenyl)-2'-deoxyguanosine (mAG) subunits. The azido-substituted mAG subunits were covalently linked to alkynyl polyester dendrons using a copper-catalyzed 1,3-dipolar cycloaddition reaction. Discrete SADs are formed with high fidelity and thermal stability even with the increased steric hindrance offered by the dendrons.

SUBMITTER: Betancourt JE 

PROVIDER: S-EPMC2654094 | biostudies-literature |

REPOSITORIES: biostudies-literature

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