Ontology highlight
ABSTRACT:
SUBMITTER: Herpin A
PROVIDER: S-EPMC2655695 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Herpin Amaury A Nakamura Shuhei S Wagner Toni U TU Tanaka Minoru M Schartl Manfred M
Nucleic acids research 20090112 5
Differential gene expression largely accounts for the coordinated manifestation of the genetic programme underlying embryonic development and cell differentiation. The 3' untranslated region (3'-UTR) of eukaryotic genes can contain motifs involved in regulation of gene expression at the post-transcriptional level. In the 3'-UTR of dmrt1, a key gene that functions in gonad development and differentiation, an 11-bp protein-binding motif was identified that mediates gonad-specific mRNA localization ...[more]