Ontology highlight
ABSTRACT:
SUBMITTER: MacMillan ML
PROVIDER: S-EPMC2656268 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
MacMillan Margaret L ML Weisdorf Daniel J DJ Brunstein Claudio G CG Cao Qing Q DeFor Todd E TE Verneris Michael R MR Blazar Bruce R BR Wagner John E JE
Blood 20081107 11
Acute graft-versus-host disease (GVHD) occurs less frequently after umbilical cord blood transplantation (UCBT). More recent investigations include the use of 2 partially human leukocyte antigen (HLA)-matched UCB units, or double UCB graft, to meet the minimum cell-dose requirement. The purpose of this analysis was to assess the relative risk of acute GVHD in 265 consecutive patients receiving transplants with UCB graft composed of 1 (n = 80) or 2 (n = 185) units. The incidence of grade III-IV a ...[more]