Ontology highlight
ABSTRACT:
SUBMITTER: Song F
PROVIDER: S-EPMC2658018 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Song Fei F Mahmood Saleh S Ghosh Srimoyee S Liang Ping P Smiraglia Domminic J DJ Nagase Hiroki H Held William A WA
Genomics 20081113 2
Tissue specific differentially methylated regions (TDMRs) were identified and localized in the mouse genome using second generation virtual RLGS (vRLGS). Sequenom MassARRAY quantitative methylation analysis was used to confirm and determine the fine structure of tissue specific differences in DNA methylation. TDMRs have a broad distribution of locations to intragenic and intergenic regions including both CpG islands, and non-CpG islands regions. Somewhat surprising, there is a strong bias for TD ...[more]