Ontology highlight
ABSTRACT:
SUBMITTER: Jayaswal V
PROVIDER: S-EPMC2658871 | biostudies-literature | 2007 Feb
REPOSITORIES: biostudies-literature
Evolutionary bioinformatics online 20070225
The non-homogeneous model of nucleotide substitution proposed by Barry and Hartigan (Stat Sci, 2: 191-210) is the most general model of DNA evolution assuming an independent and identical process at each site. We present a computational solution for this model, and use it to analyse two data sets, each violating one or more of the assumptions of stationarity, homogeneity, and reversibility. The log likelihood values returned by programs based on the F84 model (J Mol Evol, 29: 170-179), the gener ...[more]