Ontology highlight
ABSTRACT:
SUBMITTER: Murthy K
PROVIDER: S-EPMC2659544 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Journal of cell science 20080617 Pt 14
Microtubules stimulate contractile-ring formation in the equatorial cortex and simultaneously suppress contractility in the polar cortex; how they accomplish these differing activities is incompletely understood. We measured the behavior of GFP-actin in mammalian cells treated with nocodazole under conditions that either completely eliminate microtubules or selectively disassemble astral microtubules. Selective disassembly of astral microtubules resulted in functional contractile rings that were ...[more]