Ontology highlight
ABSTRACT:
SUBMITTER: Gonzalez-Juarrero M
PROVIDER: S-EPMC2660559 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Gonzalez-Juarrero Mercedes M Kingry Luke C LC Ordway Diane J DJ Henao-Tamayo Marcela M Harton Marisa M Basaraba Randall J RJ Hanneman William H WH Orme Ian M IM Slayden Richard A RA
American journal of respiratory cell and molecular biology 20080911 4
The complex molecular events that occur within the host during the establishment of a Mycobacterium tuberculosis infection are poorly defined, thus preventing identification of predictive markers of disease progression and state. To identify such molecular markers during M. tuberculosis infection, global changes in transcriptional response in the host were assessed using mouse whole genome arrays. Bacterial load in the lungs, the lesions associated with infection, and gene expression profiling w ...[more]