Ontology highlight
ABSTRACT:
SUBMITTER: Li W
PROVIDER: S-EPMC2660741 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Li Wenjing W Ferguson Brian J BJ Khaled Walid T WT Tevendale Maxine M Stingl John J Poli Valeria V Rich Tina T Salomoni Paolo P Watson Christine J CJ
Proceedings of the National Academy of Sciences of the United States of America 20090304 12
Nuclear domains of promyelocytic leukemia protein (PML) are known to act as signaling nodes in many cellular processes. Although the impact of PML expression in driving cell fate decisions for injured cells is well established, the function of PML in the context of tissue development is less well understood. Here, the in vivo role of PML in developmental processes in the murine mammary gland has been investigated. Data are presented showing that expression of PML is tightly regulated by three me ...[more]