Visualizing and quantifying adhesive signals.
Ontology highlight
ABSTRACT:
SUBMITTER: Sabouri-Ghomi M
PROVIDER: S-EPMC2661108 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
Publications
Visualizing and quantifying adhesive signals.
Sabouri-Ghomi Mohsen M Wu Yi Y Hahn Klaus K Danuser Gaudenz G
Current opinion in cell biology 20080627 5
Understanding the structural adaptation and signaling of adhesion sites in response to mechanical stimuli requires in situ characterization of the dynamic activation of a large number of adhesion components. Here, we review high-resolution live cell imaging approaches to measure forces, assembly, and interaction of adhesion components, and the activation of adhesion-mediated signals. We conclude by outlining computational multiplexing as a framework for the integration of these data into compreh ...[more]
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