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Peroxisome proliferator-activated receptors in HCV-related infection.

ABSTRACT: The topic of peroxisome proliferator-activated receptors has been developed in the field of hepatology allowing envisaging therapeutic strategies for the most frequent chronic liver diseases such as chronic infection with hepatitis C virus (HCV). PPARs contribute to wide physiological processes within the liver such as lipid/glucid metabolisms, inflammatory response, cell differentiation, and cell cycle. In vitro experiments and animal studies showed that PPAR? discloses anti-inflammatory property, and PPAR? discloses anti-inflammatory, antifibrogenic, and antiproliferative properties in the liver. Experimental and human studies showed impaired PPARs expression and function during HCV infection. The available nonhepatotoxic agonists of PPARs may constitute a progress in the therapeutic management of patients chronically infected with HCV.

SUBMITTER: Dharancy S

PROVIDER: S-EPMC2662434 | biostudies-literature | 2009

REPOSITORIES: biostudies-literature

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Peroxisome proliferator-activated receptors in HCV-related infection.

Dharancy Sébastien S Lemoine Maud M Mathurin Philippe P Serfaty Lawrence L Dubuquoy Laurent L

PPAR research 20090330

The topic of peroxisome proliferator-activated receptors has been developed in the field of hepatology allowing envisaging therapeutic strategies for the most frequent chronic liver diseases such as chronic infection with hepatitis C virus (HCV). PPARs contribute to wide physiological processes within the liver such as lipid/glucid metabolisms, inflammatory response, cell differentiation, and cell cycle. In vitro experiments and animal studies showed that PPARα discloses anti-inflammatory proper ...[more]

PMID: 19343188

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Peroxisome proliferator-activated receptors as therapeutic target for cancer.

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Peroxisome proliferator-activated

Project description: Not available

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Peroxisome proliferator-activated receptors-alpha modulate dopamine cell activity through nicotinic receptors.

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Peroxisome Proliferator-Activated Receptors Associated with Nonalcoholic Fatty Liver Disease.

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Bladder cancer associated mutations in RXRA activate peroxisome proliferator-activated receptors

Project description:This SuperSeries is composed of the SubSeries listed below.

2017-12-07 | GSE107783 | GEO

Meta-analysis of primary target genes of peroxisome proliferator-activated receptors.

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| S-EPMC2323243 | biostudies-literature

The Role of Peroxisome Proliferator-Activated Receptors (PPARs) in Pan-Cancer.

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