Ontology highlight
ABSTRACT:
SUBMITTER: Peyton KJ
PROVIDER: S-EPMC2662760 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Peyton Kelly J KJ Ensenat Diana D Azam Mohammed A MA Keswani Amit N AN Kannan Sankaranarayanan S Liu Xiao-ming XM Wang Hong H Tulis David A DA Durante William W
Arteriosclerosis, thrombosis, and vascular biology 20090122 4
<h4>Objective</h4>Arginase stimulates the proliferation of cultured vascular smooth muscle cells (VSMCs); however, the influence of arginase on VSMC growth in vivo is not known. This study investigated the impact of arginase on cell cycle progression and neointima formation after experimental arterial injury.<h4>Methods and results</h4>Balloon injury of rat carotid arteries resulted in a sustained increase in arginase activity in the vessel wall and the induction of arginase I protein in both th ...[more]