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A blaVEB-1 variant, blaVEB-6, associated with repeated elements in a complex genetic structure.


ABSTRACT: bla(VEB-6) was found on the Proteus mirabilis chromosome in a context similar to those of bla(VEB-1a) and bla(VEB-1b), in a truncated gene cassette flanked by 135-bp elements and duplications of the 3'-conserved segment of class 1 integrons. A linked aacA4-aadB-dfrA1-orfC cassette array includes components of Tn1331, illustrating the complex mosaicism of multiresistance regions.

SUBMITTER: Zong Z 

PROVIDER: S-EPMC2663121 | biostudies-literature | 2009 Apr

REPOSITORIES: biostudies-literature

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A blaVEB-1 variant, blaVEB-6, associated with repeated elements in a complex genetic structure.

Zong Zhiyong Z   Partridge Sally R SR   Iredell Jonathan R JR  

Antimicrobial agents and chemotherapy 20090112 4


bla(VEB-6) was found on the Proteus mirabilis chromosome in a context similar to those of bla(VEB-1a) and bla(VEB-1b), in a truncated gene cassette flanked by 135-bp elements and duplications of the 3'-conserved segment of class 1 integrons. A linked aacA4-aadB-dfrA1-orfC cassette array includes components of Tn1331, illustrating the complex mosaicism of multiresistance regions. ...[more]

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