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Origin of enantioselectivity in CF3-PIP-catalyzed kinetic resolution of secondary benzylic alcohols.

ABSTRACT: Computational studies provide support for the involvement of intermolecular pi-interactions in the chiral recognition of secondary benzylic alcohols by the enantioselective acyl transfer catalyst CF3-PIP.

SUBMITTER: Li X

PROVIDER: S-EPMC2663394 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature

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Origin of enantioselectivity in CF3-PIP-catalyzed kinetic resolution of secondary benzylic alcohols.

Li Ximin X Liu Peng P Houk K N KN Birman Vladimir B VB

Journal of the American Chemical Society 20080926 42

Computational studies provide support for the involvement of intermolecular pi-interactions in the chiral recognition of secondary benzylic alcohols by the enantioselective acyl transfer catalyst CF3-PIP. ...[more]

PMID: 18817392

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