Ontology highlight
ABSTRACT:
SUBMITTER: Kaab S
PROVIDER: S-EPMC2663727 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Kääb Stefan S Darbar Dawood D van Noord Charlotte C Dupuis Josée J Pfeufer Arne A Newton-Cheh Christopher C Schnabel Renate R Makino Seiko S Sinner Moritz F MF Kannankeril Prince J PJ Beckmann Britt M BM Choudry Subbarao S Donahue Brian S BS Heeringa Jan J Perz Siegfried S Lunetta Kathryn L KL Larson Martin G MG Levy Daniel D MacRae Calum A CA Ruskin Jeremy N JN Wacker Annette A Schömig Albert A Wichmann H-Erich HE Steinbeck Gerhard G Meitinger Thomas T Uitterlinden André G AG Witteman Jacqueline C M JC Roden Dan M DM Benjamin Emelia J EJ Ellinor Patrick T PT
European heart journal 20090113 7
<h4>Aims</h4>A recent genome-wide association study identified a haplotype block on chromosome 4q25 associated with atrial fibrillation (AF). We sought to replicate this association in four independent cohorts.<h4>Methods and results</h4>The Framingham Heart Study and Rotterdam Study are community-based longitudinal studies. The Vanderbilt AF Registry and German AF Network (AFNet) are case-control studies. Participants with AF (n = 3508) were more likely to be male and were older than referent p ...[more]