Ontology highlight
ABSTRACT:
SUBMITTER: Aton SJ
PROVIDER: S-EPMC2665998 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Neuron 20090201 3
Sleep is thought to consolidate changes in synaptic strength, but the underlying mechanisms are unknown. We investigated the cellular events involved in this process during ocular dominance plasticity (ODP)-a canonical form of in vivo cortical plasticity triggered by monocular deprivation (MD) and consolidated by sleep via undetermined, activity-dependent mechanisms. We find that sleep consolidates ODP primarily by strengthening cortical responses to nondeprived eye stimulation. Consolidation is ...[more]