Ontology highlight
ABSTRACT:
SUBMITTER: Schiess R
PROVIDER: S-EPMC2667347 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Schiess Ralph R Mueller Lukas N LN Schmidt Alexander A Mueller Markus M Wollscheid Bernd B Aebersold Ruedi R
Molecular & cellular proteomics : MCP 20081125 4
We present a mass spectrometry-based strategy for the specific detection and quantification of cell surface proteome changes. The method is based on the label-free quantification of peptide patterns acquired by high mass accuracy mass spectrometry using new software tools and the cell surface capturing technology that selectively enriches glycopeptides exposed to the cell exterior. The method was applied to monitor dynamic protein changes in the cell surface glycoproteome of Drosophila melanogas ...[more]