Ontology highlight
ABSTRACT:
SUBMITTER: Alders M
PROVIDER: S-EPMC2667995 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Alders Marielle M Koopmann Tamara T TT Christiaans Imke I Postema Pieter G PG Beekman Leander L Tanck Michael W T MW Zeppenfeld Katja K Loh Peter P Koch Karel T KT Demolombe Sophie S Mannens Marcel M A M MM Bezzina Connie R CR Wilde Arthur A M AA
American journal of human genetics 20090312 4
Idiopathic Ventricular Fibrillation (IVF) is defined as spontaneous VF without any known structural or electrical heart disease. A family history is present in up to 20% of probands with the disorder, suggesting that at least a subset of IVF is hereditary. A genome-wide haplotype-sharing analysis was performed for identification of the responsible gene in three distantly related families in which multiple individuals died suddenly or were successfully resuscitated at young age. We identified a h ...[more]