COTRASIF: conservation-aided transcription-factor-binding site finder.
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ABSTRACT:
SUBMITTER: Tokovenko B
PROVIDER: S-EPMC2673430 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Publications
COTRASIF: conservation-aided transcription-factor-binding site finder.
Tokovenko Bogdan B Golda Rostyslav R Protas Oleksiy O Obolenskaya Maria M El'skaya Anna A
Nucleic acids research 20090305 7
COTRASIF is a web-based tool for the genome-wide search of evolutionary conserved regulatory regions (transcription factor-binding sites, TFBS) in eukaryotic gene promoters. Predictions are made using either a position-weight matrix search method, or a hidden Markov model search method, depending on the availability of the matrix and actual sequences of the target TFBS. COTRASIF is a fully integrated solution incorporating both a gene promoter database (based on the regular Ensembl genome annota ...[more]
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