Ontology highlight
ABSTRACT:
SUBMITTER: Anum EA
PROVIDER: S-EPMC2673455 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Placenta 20090118 3
To identify candidate genes contributing to preterm birth, we examined the existing literature on the association between known disorders of connective tissue synthesis and metabolism and related diseases and prematurity. Our hypothesis was that abnormal matrix metabolism contributes to prematurity by increasing risk of preterm premature rupture of membranes (PPROM) and cervical incompetence. Based on this review, we identified gene mutations inherited by the fetus that could predispose to prete ...[more]