SBF transcription factor complex positively regulates UV mutagenesis in Saccharomyces cerevisiae.
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ABSTRACT:
SUBMITTER: Gong J
PROVIDER: S-EPMC2674285 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Publications
SBF transcription factor complex positively regulates UV mutagenesis in Saccharomyces cerevisiae.
Biochemical and biophysical research communications 20090114 4
The collection of gene deletion mutants of Saccharomyces cerevisiae was used to screen for novel genes required for UV-induced mutagenesis. We found the SBF transcription factor (Swi4/Swi6 protein complex) to be required for wild-type levels of UV mutability in forward and reverse mutation assays. Expression of translesion polymerase zeta component Rev7 was identified as a target of SBF-dependent regulation. ...[more]
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