Ontology highlight
ABSTRACT:
SUBMITTER: Norman PJ
PROVIDER: S-EPMC2675964 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
Norman Paul J PJ Abi-Rached Laurent L Gendzekhadze Ketevan K Hammond John A JA Moesta Achim K AK Sharma Deepti D Graef Thorsten T McQueen Karina L KL Guethlein Lisbeth A LA Carrington Christine V F CV Chandanayingyong Dasdayanee D Chang Yih-Hsin YH Crespí Catalina C Saruhan-Direskeneli Güher G Hameed Kamran K Kamkamidze Giorgi G Koram Kwadwo A KA Layrisse Zulay Z Matamoros Nuria N Milà Joan J Park Myoung Hee MH Pitchappan Ramasamy M RM Ramdath D Dan DD Shiau Ming-Yuh MY Stephens Henry A F HA Struik Siske S Tyan Dolly D Verity David H DH Vaughan Robert W RW Davis Ronald W RW Fraser Patricia A PA Riley Eleanor M EM Ronaghi Mostafa M Parham Peter P
Genome research 20090501 5
Natural killer (NK) cells contribute to the essential functions of innate immunity and reproduction. Various genes encode NK cell receptors that recognize the major histocompatibility complex (MHC) Class I molecules expressed by other cells. For primate NK cells, the killer-cell immunoglobulin-like receptors (KIR) are a variable and rapidly evolving family of MHC Class I receptors. Studied here is KIR3DL1/S1, which encodes receptors for highly polymorphic human HLA-A and -B and comprises three a ...[more]