Ontology highlight
ABSTRACT:
SUBMITTER: Morales AA
PROVIDER: S-EPMC2676019 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
Morales Alejo A AA Gutman Delia D Cejas Pedro J PJ Lee Kelvin P KP Boise Lawrence H LH
The Journal of biological chemistry 20090311 19
Arsenicals are both environmental carcinogens as well as therapeutic agents for the treatment of trypanosomiasis and more recently cancer. Arsenic trioxide (ATO) has been successfully used for the treatment of acute promyelocytic leukemia (APL) and has activity in multiple myeloma (MM). While signaling events associated with carcinogenesis have been well studied, it still remains to be determined which of these events are involved in anti-cancer signaling. To better define this response, gene ex ...[more]