Estimating accuracy of RNA-Seq and microarrays with proteomics.
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ABSTRACT:
SUBMITTER: Fu X
PROVIDER: S-EPMC2676304 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
Publications
Estimating accuracy of RNA-Seq and microarrays with proteomics.
Fu Xing X Fu Ning N Guo Song S Yan Zheng Z Xu Ying Y Hu Hao H Menzel Corinna C Chen Wei W Li Yixue Y Zeng Rong R Khaitovich Philipp P
BMC genomics 20090416
<h4>Background</h4>Microarrays revolutionized biological research by enabling gene expression comparisons on a transcriptome-wide scale. Microarrays, however, do not estimate absolute expression level accurately. At present, high throughput sequencing is emerging as an alternative methodology for transcriptome studies. Although free of many limitations imposed by microarray design, its potential to estimate absolute transcript levels is unknown.<h4>Results</h4>In this study, we evaluate relative ...[more]
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