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ABSTRACT: Motivation
Identification of genes coding for ribosomal RNA (rRNA) is considered an important goal in the analysis of data from metagenomics projects. Here, we report the development of a software program designed for the identification of rRNA genes from metagenomic fragments based on hidden Markov models (HMMs). This program provides rRNA gene predictions with high sensitivity and specificity on artificially fragmented genomic DNAs.Availability
Supplementary files, scripts and sample data are available at http://tools.camera.calit2.net/camera/meta_rna.
SUBMITTER: Huang Y
PROVIDER: S-EPMC2677747 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
Huang Ying Y Gilna Paul P Li Weizhong W
Bioinformatics (Oxford, England) 20090403 10
<h4>Motivation</h4>Identification of genes coding for ribosomal RNA (rRNA) is considered an important goal in the analysis of data from metagenomics projects. Here, we report the development of a software program designed for the identification of rRNA genes from metagenomic fragments based on hidden Markov models (HMMs). This program provides rRNA gene predictions with high sensitivity and specificity on artificially fragmented genomic DNAs.<h4>Availability</h4>Supplementary files, scripts and ...[more]