Ontology highlight
ABSTRACT:
SUBMITTER: Cheng CY
PROVIDER: S-EPMC2679192 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
Cheng Ching-Yu CY Kao W H Linda WH Patterson Nick N Tandon Arti A Haiman Christopher A CA Harris Tamara B TB Xing Chao C John Esther M EM Ambrosone Christine B CB Brancati Frederick L FL Coresh Josef J Press Michael F MF Parekh Rulan S RS Klag Michael J MJ Meoni Lucy A LA Hsueh Wen-Chi WC Fejerman Laura L Pawlikowska Ludmila L Freedman Matthew L ML Jandorf Lina H LH Bandera Elisa V EV Ciupak Gregory L GL Nalls Michael A MA Akylbekova Ermeg L EL Orwoll Eric S ES Leak Tennille S TS Miljkovic Iva I Li Rongling R Ursin Giske G Bernstein Leslie L Ardlie Kristin K Taylor Herman A HA Boerwinckle Eric E Zmuda Joseph M JM Henderson Brian E BE Wilson James G JG Reich David D
PLoS genetics 20090522 5
The prevalence of obesity (body mass index (BMI) > or =30 kg/m(2)) is higher in African Americans than in European Americans, even after adjustment for socioeconomic factors, suggesting that genetic factors may explain some of the difference. To identify genetic loci influencing BMI, we carried out a pooled analysis of genome-wide admixture mapping scans in 15,280 African Americans from 14 epidemiologic studies. Samples were genotyped at a median of 1,411 ancestry-informative markers. After adju ...[more]