Ontology highlight
ABSTRACT:
SUBMITTER: Schmid MF
PROVIDER: S-EPMC2680136 | biostudies-literature | 2008 Mar
REPOSITORIES: biostudies-literature
Schmid Michael F MF Booth Christopher R CR
Journal of structural biology 20071001 3
The visibility and resolution of a tomographic reconstruction containing multiple copies of discrete particles can be enhanced by averaging subtomograms after they are corrected aligned. However, the "missing wedge" in electron tomography can easily lead to erroneous alignment. We have explored a Fourier space cross-correlation method with a proper weighting scheme to align and average different sets of volumetric data, each of which has different missing data due to the limited specimen tilts. ...[more]