Variations in ceftazidime and amoxicillin-clavulanate susceptibilities within a clonal infection of Burkholderia pseudomallei.
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ABSTRACT:
SUBMITTER: Sam IC
PROVIDER: S-EPMC2681875 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
Publications
Variations in ceftazidime and amoxicillin-clavulanate susceptibilities within a clonal infection of Burkholderia pseudomallei.
Sam I-Ching IC See Kah Heng KH Puthucheary Savithri D SD
Journal of clinical microbiology 20090318 5
A patient with a clonal infection of Burkholderia pseudomallei had subpopulations with ceftazidime and amoxicillin-clavulanate susceptibilities that differed among the clinical specimens. Resistance was associated with a novel Cys69Tyr substitution in the Ambler class A beta-lactamase. Susceptibility testing of multiple colony variants from different sites should be performed for patients with culture-confirmed melioidosis. ...[more]
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