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Synergy Disequilibrium Plots: graphical visualization of pairwise synergies and redundancies of SNPs with respect to a phenotype.


ABSTRACT: We present a visualization tool applied on genome-wide association data, revealing disease-associated haplotypes, epistatically interacting loci, as well as providing visual signatures of multivariate correlations of genetic markers with respect to a phenotype.Freely available on the web at: (http://www.ee.columbia.edu/~anastas/sdplots).

SUBMITTER: Watkinson J 

PROVIDER: S-EPMC2682510 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature

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Synergy Disequilibrium Plots: graphical visualization of pairwise synergies and redundancies of SNPs with respect to a phenotype.

Watkinson John J   Anastassiou Dimitris D  

Bioinformatics (Oxford, England) 20090317 11


<h4>Summary</h4>We present a visualization tool applied on genome-wide association data, revealing disease-associated haplotypes, epistatically interacting loci, as well as providing visual signatures of multivariate correlations of genetic markers with respect to a phenotype.<h4>Availability</h4>Freely available on the web at: (http://www.ee.columbia.edu/~anastas/sdplots). ...[more]

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